Design, synthesis and initial characterisation of a radiolabelled [ 18 F]pyrimidoindolone probe for detecting activated caspase-3/7

Udemba A, Smith G, Nguyen Q-D, Kaliszczak M, Carroll L, Fortt R, Fuchter MJ, Aboagye EO

21 May 2015

Journal article

Journal:

Organic & Biomolecular Chemistry

Volume:

Issue:

Royal Society of Chemistry (RSC)

pp.

5418 - 5423

No abstract available

Keywords:

3404 Medicinal and Biomolecular Chemistry

3405 Organic Chemistry

34 Chemical Sciences

Cancer

4.2 Evaluation of markers and technologies

Cancer

Alkynes

Animals

Caco-2 Cells

Caspase 3

Caspase 7

Chromatography, High Pressure Liquid

Enzyme Activation

Humans

Indoles

Inhibitory Concentration 50

Liver

Mice

Models, Biological

Pyrimidines

Tissue Distribution

DOI